Reaction Details Report a problem with these data
Target
Lactoperoxidase
Ligand
BDBM114830
Substrate
n/a
Meas. Tech.
ChEMBL_929729 (CHEMBL3073038)
IC50
>200000±n/a nM
Citation
  TBA Med Chem Res 22:4810-4817 (2013)    Article 
Target
Name:
Lactoperoxidase
Synonyms:
LPO | Lactoperoxidase (LPO) | PERL_BOVIN
Type:
Enzyme
Mol. Mass.:
80659.97
Organism:
Bos taurus (Bovine)
Description:
P80025
Residue:
712
Sequence:
MWVCLQLPVFLASVTLFEVAASDTIAQAASTTTISDAVSKVKIQVNKAFLDSRTRLKTTLSSEAPTTQQLSEYFKHAKGRTRTAIRNGQVWEESLKRLRRDTTLTNVTDPSLDLTALSWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
  
Inhibitor
Name:
BDBM114830
Synonyms:
3-(4-methoxyphenyl)-1H-isochromen-1-one | 3-(4-methoxyphenyl)-2-benzopyran-1-one | 3-(4-methoxyphenyl)isochromen-1-one | 3-(4-methoxyphenyl)isocoumarin | MLS001360841 | SMR000743609 | cid_275900
Type:
Small organic molecule
Emp. Form.:
C16H12O3
Mol. Mass.:
252.2647
SMILES:
COc1ccc(cc1)-c1cc2ccccc2c(=O)o1
Structure:
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