Reaction Details Report a problem with these data
Target
Growth factor receptor-bound protein 2
Ligand
BDBM50489113
Substrate
n/a
Meas. Tech.
ChEMBL_930651 (CHEMBL3068865)
Kd
6.3±n/a nM
Citation
  TBA Med Chem Res 22:5337-5343 (2013)    Article 
Target
Name:
Growth factor receptor-bound protein 2
Synonyms:
ASH | GRB2 | GRB2 adapter protein | GRB2_HUMAN | Grb2-SH2 | Growth factor receptor-bound protein 2
Type:
Protein
Mol. Mass.:
25205.04
Organism:
Homo sapiens (Human)
Description:
P62993
Residue:
217
Sequence:
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
  
Inhibitor
Name:
BDBM50489113
Synonyms:
CHEMBL2296610
Type:
Small organic molecule
Emp. Form.:
C37H41N5O11
Mol. Mass.:
731.7483
SMILES:
CC(C)(NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(O)=O |r|
Structure:
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