Reaction Details Report a problem with these data
Target
Anthrax toxin receptor 2
Ligand
BDBM50337364
Substrate
n/a
Meas. Tech.
ChEMBL_938547 (CHEMBL2327386)
IC50
>300000±n/a nM
Citation
 Cryan, LM; Bazinet, L; Habeshian, KA; Cao, S; Clardy, J; Christensen, KA; Rogers, MS 1,2,3,4,6-Penta-O-galloyl-?-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2. J Med Chem 56:1940-5 (2013) [PubMed]  Article 
Target
Name:
Anthrax toxin receptor 2
Synonyms:
ANTR2_HUMAN | ANTXR2 | Anthrax toxin receptor 2 | CMG-2 | CMG2 | Capillary morphogenesis gene 2 protein
Type:
PROTEIN
Mol. Mass.:
53667.55
Organism:
Homo sapiens
Description:
ChEMBL_118453
Residue:
489
Sequence:
MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEVCIWECIEKELTA
  
Inhibitor
Name:
BDBM50337364
Synonyms:
3-methoxy-4-hydroxybenzoic acid | 4-Hydroxy-3-methoxy-benzoic acid | 4-hydroxy-3-methoxybenzoic acid | 4-hydroxyl-3-methoxybenzoic acid | CHEMBL120568 | Vanilic acid | Vanillic acid (M2)
Type:
Small organic molecule
Emp. Form.:
C8H8O4
Mol. Mass.:
168.1467
SMILES:
COc1cc(ccc1O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: