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Target
Anthrax toxin receptor 2
Ligand
BDBM50242283
Substrate
n/a
Meas. Tech.
ChEMBL_938547 (CHEMBL2327386)
IC50
>300000±n/a nM
Citation
 Cryan, LM; Bazinet, L; Habeshian, KA; Cao, S; Clardy, J; Christensen, KA; Rogers, MS 1,2,3,4,6-Penta-O-galloyl-?-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2. J Med Chem 56:1940-5 (2013) [PubMed]  Article 
Target
Name:
Anthrax toxin receptor 2
Synonyms:
ANTR2_HUMAN | ANTXR2 | Anthrax toxin receptor 2 | CMG-2 | CMG2 | Capillary morphogenesis gene 2 protein
Type:
PROTEIN
Mol. Mass.:
53667.55
Organism:
Homo sapiens
Description:
ChEMBL_118453
Residue:
489
Sequence:
MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEVCIWECIEKELTA
  
Inhibitor
Name:
BDBM50242283
Synonyms:
3,4-dihydroxymethylbenzoate | CHEMBL486027 | Methyl protocatechuate | methyl 3,4-dihydroxybenzoate
Type:
Small organic molecule
Emp. Form.:
C8H8O4
Mol. Mass.:
168.1467
SMILES:
COC(=O)c1ccc(O)c(O)c1
Structure:
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