Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM50428380
Substrate
n/a
Meas. Tech.
ChEMBL_958851 (CHEMBL2384639)
EC50
1860±n/a nM
Citation
 Cao, X; Jiang, J; Zhang, S; Zhu, L; Zou, J; Diao, Y; Xiao, W; Shan, L; Sun, H; Zhang, W; Huang, J; Li, H Discovery of natural estrogen receptor modulators with structure-based virtual screening. Bioorg Med Chem Lett 23:3329-33 (2013) [PubMed]  Article 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM50428380
Synonyms:
E214 | ETHYLPARABEN | Ethyl Parahydroxybenzoate
Type:
Small organic molecule
Emp. Form.:
C9H10O3
Mol. Mass.:
166.1739
SMILES:
CCOC(=O)c1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: