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Target
Glutamyl aminopeptidase
Ligand
BDBM50036965
Substrate
n/a
Meas. Tech.
ChEMBL_32829 (CHEMBL646207)
Ki
1600±n/a nM
Citation
 Chauvel, EN; Llorens-Cortès, C; Coric, P; Wilk, S; Roques, BP; Fournié-Zaluski, MC Differential inhibition of aminopeptidase A and aminopeptidase N by new beta-amino thiols. J Med Chem 37:2950-7 (1994) [PubMed]  Article 
Target
Name:
Glutamyl aminopeptidase
Synonyms:
AMPE_HUMAN | AP-A | Aminopeptidase A | CD_antigen=CD249 | Differentiation antigen gp160 | EAP | ENPEP | Glutamyl aminopeptidase
Type:
PROTEIN
Mol. Mass.:
109226.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_32829
Residue:
957
Sequence:
MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGGPGTAPAPSHLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLLESG
  
Inhibitor
Name:
BDBM50036965
Synonyms:
5-Carboxy-1-mercaptomethyl-pentyl-ammonium | 6-Amino-7-mercapto-heptanoic acid | CHEMBL100140
Type:
Small organic molecule
Emp. Form.:
C7H15NO2S
Mol. Mass.:
177.265
SMILES:
NC(CS)CCCCC(O)=O
Structure:
Search PDB for entries with ligand similarity: