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Target
Mu-type opioid receptor
Ligand
BDBM50492547
Substrate
n/a
Meas. Tech.
ChEMBL_972711 (CHEMBL2410920)
Ki
3.3±n/a nM
Citation
 Lesma, G; Salvadori, S; Airaghi, F; Murray, TF; Recca, T; Sacchetti, A; Balboni, G; Silvani, A Structural and biological exploration of phe(3)-phe(4)-modified endomorphin-2 peptidomimetics. ACS Med Chem Lett 4:795-9 (2013) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50492547
Synonyms:
CHEMBL2409169
Type:
Small organic molecule
Emp. Form.:
C36H42F3N5O7
Mol. Mass.:
713.7432
SMILES:
OC(=O)C(F)(F)F.N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CC(=O)NC[C@H](Cc1ccccc1)C(N)=O)Cc1ccccc1 |r|
Structure:
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