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Target
Low molecular weight protein-tyrosine phosphatase A
Ligand
BDBM50341977
Substrate
n/a
Meas. Tech.
ChEMBL_984414 (CHEMBL2433138)
Ki
1600±n/a nM
Citation
 Cooper, CB Development of Mycobacterium tuberculosis whole cell screening hits as potential antituberculosis agents. J Med Chem 56:7755-60 (2013) [PubMed]  Article 
Target
Name:
Low molecular weight protein-tyrosine phosphatase A
Synonyms:
PTPA_MYCTU | PTPase | Probable low molecular weight protein-tyrosine-phosphatase | Protein Tyrosine Phosphatase PTPA | mptpA | ptpA
Type:
Hydrolase
Mol. Mass.:
17891.84
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
163
Sequence:
MSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGLHDWVDERLARNGPS
  
Inhibitor
Name:
BDBM50341977
Synonyms:
2-(2,5-dimethyl-1H-pyrrol-1-yl)-5-hydroxybenzoic acid | CHEMBL1765360
Type:
Small organic molecule
Emp. Form.:
C13H13NO3
Mol. Mass.:
231.2472
SMILES:
Cc1ccc(C)n1-c1ccc(O)cc1C(O)=O |(5.57,-.15,;4.1,-.62,;3.62,-2.09,;2.08,-2.09,;1.61,-.62,;.14,-.15,;2.86,.28,;2.85,1.82,;1.51,2.59,;1.51,4.14,;2.84,4.91,;2.84,6.45,;4.18,4.14,;4.18,2.59,;5.66,2.2,;6.75,3.29,;6.06,.71,)|
Structure:
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