Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50494431
Substrate
n/a
Meas. Tech.
ChEMBL_1274849 (CHEMBL3090423)
Ki
3.7±n/a nM
Citation
 Dal Ben, D; Buccioni, M; Lambertucci, C; Thomas, A; Klotz, KN; Federico, S; Cacciari, B; Spalluto, G; Volpini, R 8-(2-Furyl)adenine derivatives as A?A adenosine receptor ligands. Eur J Med Chem 70:525-35 (2013) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50494431
Synonyms:
CHEMBL3087715
Type:
Small organic molecule
Emp. Form.:
C11H11N5O
Mol. Mass.:
229.2379
SMILES:
CCn1c(nc2c(N)ncnc12)-c1ccco1
Structure:
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