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Target
Carbonic anhydrase 7
Ligand
BDBM10883
Substrate
n/a
Meas. Tech.
ChEMBL_1281628 (CHEMBL3102438)
Ki
27±n/a nM
Citation
 De Luca, L; Ferro, S; Damiano, FM; Supuran, CT; Vullo, D; Chimirri, A; Gitto, R Structure-based screening for the discovery of new carbonic anhydrase VII inhibitors. Eur J Med Chem 71:105-11 (2014) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM10883
Synonyms:
4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 | Dichlorophenamide | Dichlorophenamide (DCP) | Dichlorophenamide, DCP | Sulfonamide, 4 | US10172837, Dichlorphenamide | sulfonamide 4
Type:
Small organic molecule
Emp. Form.:
C6H6Cl2N2O4S2
Mol. Mass.:
305.159
SMILES:
NS(=O)(=O)c1cc(Cl)c(Cl)c(c1)S(N)(=O)=O
Structure:
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