Reaction Details Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM50495074
Substrate
n/a
Meas. Tech.
ChEMBL_1282230 (CHEMBL3102455)
Ki
1.8±n/a nM
Citation
 Martín-Gago, P; Ramón, R; Aragón, E; Fernández-Carneado, J; Martin-Malpartida, P; Verdaguer, X; López-Ruiz, P; Colás, B; Cortes, MA; Ponsati, B; Macias, MJ; Riera, A A tetradecapeptide somatostatin dicarba-analog: Synthesis, structural impact and biological activity. Bioorg Med Chem Lett 24:103-7 (2014) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50495074
Synonyms:
CHEMBL3098601
Type:
Small organic molecule
Emp. Form.:
C78H107N19O18
Mol. Mass.:
1598.8007
SMILES:
[H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C\C=C/C[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r,c:73|
Structure:
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