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Target
Cannabinoid receptor 2
Ligand
BDBM50495106
Substrate
n/a
Meas. Tech.
ChEMBL_1285977 (CHEMBL3106284)
Ki
6.3±n/a nM
Citation
 Sharma, R; Nikas, SP; Paronis, CA; Wood, JT; Halikhedkar, A; Guo, JJ; Thakur, GA; Kulkarni, S; Benchama, O; Raghav, JG; Gifford, RS; Järbe, TU; Bergman, J; Makriyannis, A Controlled-deactivation cannabinergic ligands. J Med Chem 56:10142-57 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50495106
Synonyms:
CHEMBL3104358 | US10882838, Example 1.16
Type:
Small organic molecule
Emp. Form.:
C23H32O4
Mol. Mass.:
372.4978
SMILES:
[H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)[C@H](C)C(=O)OCCCC |r,c:4|
Structure:
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