Reaction Details Report a problem with these data
Target
Genome polyprotein
Ligand
BDBM50496205
Substrate
n/a
Meas. Tech.
ChEMBL_1294623 (CHEMBL3128538)
Ki
110±n/a nM
Citation
Lampa, AK; Bergman, SM; Gustafsson, SS; Alogheli, H; Akerblom, EB; Lindeberg, GG; Svensson, RM; Artursson, P; Danielson, UH; Karlén, A; Sandström, A Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2-P1' Region. ACS Med Chem Lett 5:249-54 (2014) [PubMed] Article
More Info.:
Target
Name:
Genome polyprotein
Synonyms:
NS3 protease
Type:
PROTEIN
Mol. Mass.:
19154.35
Organism:
Hepacivirus C
Description:
ChEMBL_118440
Residue:
181
Sequence:
APITAYAQQTRGLLGCIITSLTGRDKNQAEGEVQIVSTATQTFLATCINGVCWTVYHGAGTRTIASPKGPVIQMYTNVDKDLVGWPAPQGTRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVENLETTMRS