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Target
MBT domain-containing protein 1
Ligand
BDBM50440614
Substrate
n/a
Meas. Tech.
ChEMBL_1300218 (CHEMBL3136682)
IC50
78000±n/a nM
Citation
 Camerino, MA; Zhong, N; Dong, A; Dickson, BM; James, LI; Baughman, BM; Norris, JL; Kireev, DB; Janzen, WP; Arrowsmith, CH; Frye, SV The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface. Medchemcomm 4:1501-1507 (2013) [PubMed]  Article 
Target
Name:
MBT domain-containing protein 1
Synonyms:
MBT domain-containing protein 1 | MBT domain-containing protein 1 (MBTD1) | MBTD1 | MBTD1_HUMAN
Type:
Protein
Mol. Mass.:
70557.67
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
628
Sequence:
MFDGYDSCSEDTSSSSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVSMEGFSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKKMTTLQLKEELLDGEDYNFLQGASDQESNGSANFYIKQEP
  
Inhibitor
Name:
BDBM50440614
Synonyms:
CHEMBL2426364
Type:
Small organic molecule
Emp. Form.:
C32H43N5O2
Mol. Mass.:
529.7161
SMILES:
O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Nc2ccccc2)c1
Structure:
Search PDB for entries with ligand similarity: