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Target
Lethal(3)malignant brain tumor-like protein 1
Ligand
BDBM50496582
Substrate
n/a
Meas. Tech.
ChEMBL_1300219 (CHEMBL3136683)
IC50
92000±n/a nM
Citation
 Camerino, MA; Zhong, N; Dong, A; Dickson, BM; James, LI; Baughman, BM; Norris, JL; Kireev, DB; Janzen, WP; Arrowsmith, CH; Frye, SV The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface. Medchemcomm 4:1501-1507 (2013) [PubMed]  Article 
Target
Name:
Lethal(3)malignant brain tumor-like protein 1
Synonyms:
H-l(3)mbt | H-l(3)mbt protein | KIAA0681 | L(3)mbt protein homolog | L(3)mbt-like | L3MBT | L3MBTL | L3MBTL1 | LMBL1_HUMAN
Type:
PROTEIN
Mol. Mass.:
92284.44
Organism:
Homo sapiens
Description:
ChEMBL_103624
Residue:
840
Sequence:
MHLVAGDSPGSGPHLPATAFIIPASSATLGLPSSALDVSCFPREPIHVGAPEQVAGCEPVSATVLPQLSAGPASSSTSTVRLLEWTEAAAPPPGGGLRFRISEYKPLNMAGVEQPPSPELRQEGVTEYEDGGAPAGDGEAGPQQAEDHPQNPPEDPNQDPPEDDSTCQCQACGPHQAAGPDLGSSNDGCPQLFQERSVIVENSSGSTSASELLKPMKKRKRREYQSPSEEESEPEAMEKQEEGKDPEGQPTASTPESEEWSSSQPATGEKKECWSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRPPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGPREPSSASPGGCPPLSYRSLPHTRTSKYSFHHRKCPTPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRLKAELSDSEASARKKNLSGFSPRKKPRHHGRIGRPPKYRKIPQEDFQTLTPDVVHQSLFMSALSAHPDRSLSVCWEQHCKLLPGVAGISASTVAKWTIDEVFGFVQTLTGCEDQARLFKDEARIVRVTHVSGKTLVWTVAQLGDLVCSDHLQEGKGILETGVHSLLCSLPTHLLAKLSFASDSQY
  
Inhibitor
Name:
BDBM50496582
Synonyms:
CHEMBL3134128
Type:
Small organic molecule
Emp. Form.:
C23H35N3O2
Mol. Mass.:
385.5429
SMILES:
C(Cc1ccc(cc1)N1CCC(CC1)N1CCCC1)N1CCC2(C1)OCCO2
Structure:
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