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Target
Chromobox protein homolog 7
Ligand
BDBM50440614
Substrate
n/a
Meas. Tech.
ChEMBL_1300216 (CHEMBL3136680)
IC50
>30000±n/a nM
Citation
 Camerino, MA; Zhong, N; Dong, A; Dickson, BM; James, LI; Baughman, BM; Norris, JL; Kireev, DB; Janzen, WP; Arrowsmith, CH; Frye, SV The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface. Medchemcomm 4:1501-1507 (2013) [PubMed]  Article 
Target
Name:
Chromobox protein homolog 7
Synonyms:
CBX7 | CBX7_HUMAN | Chromobox protein homolog 7 | Chromobox protein homolog 7 (CBX7)
Type:
Protein
Mol. Mass.:
28351.76
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
251
Sequence:
MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKAGAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAPDVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAAEGFFRDRSGKF
  
Inhibitor
Name:
BDBM50440614
Synonyms:
CHEMBL2426364
Type:
Small organic molecule
Emp. Form.:
C32H43N5O2
Mol. Mass.:
529.7161
SMILES:
O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Nc2ccccc2)c1
Structure:
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