Reaction Details Report a problem with these data
Target
P2Y purinoceptor 12
Ligand
BDBM50044186
Substrate
n/a
Meas. Tech.
ChEBML_223118
IC50
9000±n/a nM
Citation
 Morris, J; Wishka, DG; Lin, AH; Humphrey, WR; Wiltse, AL; Gammill, RB; Judge, TM; Bisaha, SN; Olds, NL; Jacob, CS Synthesis and biological evaluation of antiplatelet 2-aminochromones. J Med Chem 36:2026-32 (1993) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 12
Synonyms:
ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999
Type:
Enzyme
Mol. Mass.:
39458.48
Organism:
Homo sapiens (Human)
Description:
Q9H244
Residue:
342
Sequence:
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
  
Inhibitor
Name:
BDBM50044186
Synonyms:
(8-Methyl-2-morpholin-4-yl-4-oxo-4H-chromen-7-yloxy)-acetic acid methyl ester | CHEMBL60240
Type:
Small organic molecule
Emp. Form.:
C17H19NO6
Mol. Mass.:
333.3359
SMILES:
COC(=O)COc1ccc2c(oc(cc2=O)N2CCOCC2)c1C
Structure:
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