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Target
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Ligand
BDBM50496771
Substrate
n/a
Meas. Tech.
ChEMBL_1332680 (CHEMBL3224262)
IC50
797300±n/a nM
Citation
Bitok, JK; Meyers, CF Synthesis and evaluation of stable substrate analogs as potential modulators of cyclodiphosphate synthase IspF. Medchemcomm 4:130-134 (2013) [PubMed] Article
More Info.:
Target
Name:
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Synonyms:
2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase (IspF) | ISPF_ECOLI | MECDP-synthase | MECPS | ispF | mecS | ygbB
Type:
Homotrimer
Mol. Mass.:
16897.34
Organism:
Escherichia coli (strain K12)
Description:
P62617
Residue:
159
Sequence:
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK