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Target
Choline kinase alpha
Ligand
BDBM50496846
Substrate
n/a
Meas. Tech.
ChEMBL_1329435 (CHEMBL3227789)
EC50
1300±n/a nM
Citation
 Trousil, S; Carroll, L; Kalusa, A; Aberg, O; Kaliszczak, M; Aboagye, EO Design of symmetrical and nonsymmetrical  Medchemcomm 2013:693-696 (2013) [PubMed]  Article 
Target
Name:
Choline kinase alpha
Synonyms:
CHK | CHKA | CHKA_HUMAN | CKI | Choline kinase alpha
Type:
PROTEIN
Mol. Mass.:
52248.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1290064
Residue:
457
Sequence:
MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
  
Inhibitor
Name:
BDBM50496846
Synonyms:
CHEMBL228000
Type:
Small organic molecule
Emp. Form.:
C26H44Br2N4
Mol. Mass.:
572.462
SMILES:
[Br-].[Br-].CN(C)c1cc[n+](CCCCCCCCCCCC[n+]2ccc(cc2)N(C)C)cc1
Structure:
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