Reaction Details Report a problem with these data
Target
P2Y purinoceptor 2
Ligand
BDBM50496860
Substrate
n/a
Meas. Tech.
ChEMBL_1330933 (CHEMBL3224913)
EC50
28±n/a nM
Citation
 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA 4-Alkyloxyimino-cytosine nucleotides: tethering approaches to molecular probes for the P2Y Medchemcomm 4:1156-1165 (2013) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42299.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1455361
Residue:
377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
  
Inhibitor
Name:
BDBM50496860
Synonyms:
CHEMBL1198849
Type:
Small organic molecule
Emp. Form.:
C10H18N3O15P3
Mol. Mass.:
513.1823
SMILES:
CO\N=c1/ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1 |r|
Structure:
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