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Target
Leukotriene B4 receptor 1
Ligand
BDBM50045095
Substrate
n/a
Meas. Tech.
ChEBML_99661
IC50
2097±n/a nM
Citation
 Jackson, WT; Boyd, RJ; Froelich, LL; Gapinski, DM; Mallett, BE; Sawyer, JS Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists. J Med Chem 36:1726-34 (1993) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50045095
Synonyms:
5-(2-Carboxy-ethyl)-6-decyloxy-9-oxo-9H-xanthene-4-carboxylic acid | CHEMBL49209
Type:
Small organic molecule
Emp. Form.:
C27H32O7
Mol. Mass.:
468.5388
SMILES:
CCCCCCCCCCOc1ccc2c(oc3c(cccc3c2=O)C(O)=O)c1CCC(O)=O
Structure:
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