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Target
B2 bradykinin receptor
Ligand
BDBM50045215
Substrate
n/a
Meas. Tech.
ChEBML_40275
Ki
1.5±n/a nM
Citation
 Chakravarty, S; Wilkins, D; Kyle, DJ Design of potent, cyclic peptide bradykinin receptor antagonists from conformationally constrained linear peptides. J Med Chem 36:2569-71 (1993) [PubMed]  Article 
Target
Name:
B2 bradykinin receptor
Synonyms:
B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKRB2_CAVPO | Bradykinin B2 receptor
Type:
n/a
Mol. Mass.:
42217.03
Organism:
Cavia porcellus
Description:
n/a
Residue:
372
Sequence:
MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHKSSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGHNVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTERRATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCLNPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWARSSSEGTPPGLL
  
Inhibitor
Name:
BDBM50045215
Synonyms:
CHEMBL2370010 | D-Arg-Arg-cyclo[Cys-Pro-Gly-Cys]-Ser-D-Tic-Oic-Arg
Type:
Small organic molecule
Emp. Form.:
C53H83N19O12S2
Mol. Mass.:
1242.476
SMILES:
[H][C@@]12[#6]-[#6]-[#6]-[#7]1-[#6](=O)-[#6@H](-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6]2=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-1-[#6]-c2ccccc2-[#6]-[#6@H]-1-[#6](=O)-[#7]-1-[#6]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7]
Structure:
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