Reaction Details Report a problem with these data
Target
Protein Tat
Ligand
BDBM50045403
Substrate
n/a
Meas. Tech.
ChEBML_209908
IC50
2600±n/a nM
Citation
 Michne, WF; Schroeder, JD; Bailey, TR; Young, DC; Hughes, JV; Dutko, FJ Keto/enol epoxy steroids: a new structural class of HIV-1 Tat inhibitors. J Med Chem 36:2701-2 (1993) [PubMed]  Article 
Target
Name:
Protein Tat
Synonyms:
Human immunodeficiency virus type 1 Tat protein | Protein Tat | TAT_HV112 | Transactivating regulatory protein | tat
Type:
PROTEIN
Mol. Mass.:
9771.75
Organism:
Human immunodeficiency virus type 1 (isolate PCV12 group M subtype B)(HIV-1)
Description:
ChEMBL_199318
Residue:
86
Sequence:
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAPQGSQTHQVSLSKQPTSQSRGDPTGPKE
  
Inhibitor
Name:
BDBM50045403
Synonyms:
Acetic acid 2-carbamoyl-3-hydroxy-10,13-dimethyl-1,4,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-20-oxa-cyclopropa[4,5]cyclopenta[a]phenanthren-17-yl ester | CHEMBL2373186
Type:
Small organic molecule
Emp. Form.:
C22H31NO5
Mol. Mass.:
389.4852
SMILES:
[H][C@@]12O[C@@]11CCC3C4CC[C@H](OC(C)=O)[C@@]4(C)CCC3[C@@]1(C)CC(C(N)=O)=C2O |c:30|
Structure:
Search PDB for entries with ligand similarity: