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Target
Translocator protein
Ligand
BDBM50045881
Substrate
n/a
Meas. Tech.
ChEBML_218704
Ki
476.0±n/a nM
Citation
 Kozikowski, AP; Ma, D; Brewer, J; Sun, S; Costa, E; Romeo, E; Guidotti, A Chemistry, binding affinities, and behavioral properties of a new class of"antineophobic" mitochondrial DBI receptor complex (mDRC) ligands. J Med Chem 36:2908-20 (1993) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:
Mitochondrion membrane protein
Mol. Mass.:
18945.84
Organism:
Rattus norvegicus (rat)
Description:
Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:
169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
  
Inhibitor
Name:
BDBM50045881
Synonyms:
CHEMBL98382 | N-(2-Bromo-phenyl)-2-[2-(4-fluoro-phenyl)-1H-indol-3-yl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C22H16BrFN2O
Mol. Mass.:
423.278
SMILES:
Fc1ccc(cc1)-c1[nH]c2ccccc2c1CC(=O)Nc1ccccc1Br
Structure:
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