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Target
Glycerol-3-phosphate acyltransferase 1, mitochondrial
Ligand
BDBM50498246
Substrate
n/a
Meas. Tech.
ChEMBL_1498249 (CHEMBL3583672)
IC50
10100±n/a nM
Citation
 Outlaw, VK; Wydysh, EA; Vadlamudi, A; Medghalchi, SM; Townsend, CA Design, Synthesis, and Evaluation of 4- and 5-Substituted  Medchemcomm 5:826-830 (2014) [PubMed]  Article 
Target
Name:
Glycerol-3-phosphate acyltransferase 1, mitochondrial
Synonyms:
2.3.1.15 | GPAT-1 | GPAT1_MOUSE | Glycerol-3-phosphate acyltransferase 1, mitochondrial | Gpam | Gpat1 | P90
Type:
PROTEIN
Mol. Mass.:
93718.58
Organism:
Mus musculus
Description:
ChEMBL_109810
Residue:
827
Sequence:
MEESSVTVGTIDVSYLPSSSEYSLGRCKHTSEDWVDCGFKPTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLSSSRVQEAIAEVAAELNPDGSAQQQSKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDETPDGRKDILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLEGQSQKPVSAPLSLEQALLPAILPSRPNDVADEHQDLSSNESRNPADEAFRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSIYAVLNKRCSGGSAGGLGNLISQEQLVRKAASLCYLLSNEGTISLPCQTFYQVCHETVGKFIQYGILTVAEQDDQEDVSPGLAEQQWDKKLPELNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPESEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKQKRVSVLELSSTFLPQCNRQKLLEYILSFVVL
  
Inhibitor
Name:
BDBM50498246
Synonyms:
CHEMBL3580987
Type:
Small organic molecule
Emp. Form.:
C27H31NO4S
Mol. Mass.:
465.604
SMILES:
CCCCCCCCS(=O)(=O)Nc1ccc(cc1C(O)=O)-c1ccccc1-c1ccccc1
Structure:
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