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Target
Laforin
Ligand
BDBM50498446
Substrate
n/a
Meas. Tech.
ChEMBL_1506353 (CHEMBL3599432)
IC50
56000±n/a nM
Citation
 He, R; Bai, Y; Yu, ZH; Wu, L; Gunawan, AM; Zhang, ZY Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis. Medchemcomm 5:1496-1499 (2014) [PubMed]  Article 
Target
Name:
Laforin
Synonyms:
EPM2A | EPM2A_HUMAN | LAFPTPase | Lafora PTPase | Laforin
Type:
Protein
Mol. Mass.:
37158.16
Organism:
Homo sapiens (Human)
Description:
O95278
Residue:
331
Sequence:
MRFRFGVVVPPAVAGARPELLVVGSRPELGRWEPRGAVRLRPAGTAAGDGALALQEPGLWLGEVELAAEEAAQDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDGVYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEALARAQEDFFQKFGKVRSSVCSL
  
Inhibitor
Name:
BDBM50498446
Synonyms:
CHEMBL3596431
Type:
Small organic molecule
Emp. Form.:
C14H9BrN2O3S
Mol. Mass.:
365.202
SMILES:
OC(=O)c1cc2sc(Nc3cccc(Br)c3)nc2cc1O
Structure:
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