Target
Thromboxane A2 receptor
Ligand
BDBM50047056
Substrate
n/a
Meas. Tech.
ChEMBL_207650 (CHEMBL811632)
Ki
670.0±n/a nM
Citation
 Nicolaï, EGoyard, JBenchetrit, TTeulon, JMCaussade, FVirone, ADelchambre, CCloarec, A Synthesis and structure-activity relationships of novel benzimidazole and imidazo[4,5-b]pyridine acid derivatives as thromboxane A2 receptor antagonists. J Med Chem 36:1175-87 (1993) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50047056
Synonyms:
2-[1-(4-Chloro-benzyl)-5-fluoro-1H-benzoimidazol-2-ylsulfanyl]-2-methyl-propionic acid | CHEMBL274485
Type:
Small organic molecule
Emp. Form.:
C18H16ClFN2O2S
Mol. Mass.:
378.848
SMILES:
CC(C)(Sc1nc2cc(F)ccc2n1Cc1ccc(Cl)cc1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: