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Target
Platelet-activating factor receptor
Ligand
BDBM50047758
Substrate
n/a
Meas. Tech.
ChEMBL_221702 (CHEMBL823402)
IC50
1100±n/a nM
Citation
 Trova, MP; Wissner, A; Carroll, ML; Kerwar, SS; Pickett, WC; Schaub, RE; Torley, LW; Kohler, CA Analogues of platelet activating factor. 8. Antagonists of PAF containing an aromatic ring linked to a pyridinium ring. J Med Chem 36:580-90 (1993) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50047758
Synonyms:
4-{[Acetyl-(3-tert-butyl-4-tetradecyloxy-benzoyl)-amino]-methyl}-1-methyl-pyridinium; iodide | CHEMBL154459
Type:
Small organic molecule
Emp. Form.:
C34H53N2O3
Mol. Mass.:
537.7957
SMILES:
CCCCCCCCCCCCCCOc1ccc(cc1C(C)(C)C)C(=O)N(Cc1cc[n+](C)cc1)C(C)=O
Structure:
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