Reaction Details Report a problem with these data
Target
Protein translocase subunit SecA 1
Ligand
BDBM50498947
Substrate
n/a
Meas. Tech.
ChEMBL_1540162 (CHEMBL3738517)
IC50
500±n/a nM
Citation
 Jin, J; Cui, J; Chaudhary, AS; Hsieh, YH; Damera, K; Zhang, H; Yang, H; Wang, B; Tai, PC Evaluation of small molecule SecA inhibitors against methicillin-resistant Staphylococcus aureus. Bioorg Med Chem 23:7061-8 (2015) [PubMed]  Article 
Target
Name:
Protein translocase subunit SecA 1
Synonyms:
Protein translocase subunit SecA 1 | SECA1_STAA8 | secA1
Type:
PROTEIN
Mol. Mass.:
95932.26
Organism:
Staphylococcus aureus (strain NCTC 8325)
Description:
ChEMBL_116905
Residue:
843
Sequence:
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
  
Inhibitor
Name:
BDBM50498947
Synonyms:
Rose bengal sodium
Type:
Small organic molecule
Emp. Form.:
C20H2Cl4I4Na2O5
Mol. Mass.:
1017.636
SMILES:
n/a
Structure:
Search PDB for entries with ligand similarity: