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Target
Structural capsid protein
Ligand
BDBM50500840
Substrate
n/a
Meas. Tech.
ChEMBL_1556996 (CHEMBL3772327)
IC50
4000±n/a nM
Citation
 Machara, A; Lux, V; Ko?í?ek, M; Grantz ?a?ková, K; ?t?pánek, O; Kotora, M; Parkan, K; Pávová, M; Glass, B; Sehr, P; Lewis, J; Müller, B; Kräusslich, HG; Konvalinka, J Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. J Med Chem 59:545-58 (2016) [PubMed]  Article 
Target
Name:
Structural capsid protein
Synonyms:
Structural capsid protein | gag
Type:
PROTEIN
Mol. Mass.:
12762.23
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_106648
Residue:
115
Sequence:
ELERFAVNPALLETSEGCRQILGQLQPSLQTGSEELKSLFNTVATLYCVHQRIEVKDTKEALDKIEEEQNKSKKKAQQAQQAAAATGSSQVSQNYPIVQNLQGQMVHQPISPRTL
  
Inhibitor
Name:
BDBM50500840
Synonyms:
CHEMBL3769666
Type:
Small organic molecule
Emp. Form.:
C20H13N5
Mol. Mass.:
323.3507
SMILES:
N#Cc1ccc(Nc2nc(nc3ccccc23)-c2ccncc2)cc1
Structure:
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