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Target
Matrix protein 2
Ligand
BDBM50500846
Substrate
n/a
Meas. Tech.
ChEMBL_1556436 (CHEMBL3772467)
IC50
18700±n/a nM
Citation
 Li, F; Ma, C; DeGrado, WF; Wang, J Discovery of Highly Potent Inhibitors Targeting the Predominant Drug-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel. J Med Chem 59:1207-16 (2016) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I72A8 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11180.06
Organism:
Influenza A virus (A/Udorn/307/1972(H3N2))
Description:
ChEMBL_22
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
  
Inhibitor
Name:
BDBM50500846
Synonyms:
CHEMBL3770480
Type:
Small organic molecule
Emp. Form.:
C15H26ClN
Mol. Mass.:
255.827
SMILES:
n/a
Structure:
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