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Target
Adenosine receptor A1
Ligand
BDBM50051348
Substrate
n/a
Meas. Tech.
ChEMBL_29152 (CHEMBL639432)
Ki
9090±n/a nM
Citation
 Karton, Y; Jiang, JL; Ji, XD; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. J Med Chem 39:2293-301 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50051348
Synonyms:
2-(2,4-Dihydroxy-phenyl)-5-hydroxy-7-methoxy-6-((E)-3-methyl-but-1-enyl)-3-(3-methyl-but-2-enyl)-chromen-4-one | ARTOCARPIN | CHEMBL72617
Type:
Small organic molecule
Emp. Form.:
C26H28O6
Mol. Mass.:
436.4969
SMILES:
[#6]-[#8]-c1cc2oc(c(-[#6]\[#6]=[#6](\[#6])-[#6])c(=O)c2c(-[#8])c1-[#6]=[#6]-[#6](-[#6])-[#6])-c1ccc(-[#8])cc1-[#8] |w:19.20|
Structure:
Search PDB for entries with ligand similarity: