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Target
Translocator protein
Ligand
BDBM50045877
Substrate
n/a
Meas. Tech.
ChEMBL_39280 (CHEMBL650541)
IC50
10±n/a nM
Citation
 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW (S)-(-)-4-[4-[2-(isochroman-1-yl)ethyl]-piperazin-1-yl] benzenesulfonamide, a selective dopamine D4 antagonist. J Med Chem 39:2435-7 (1996) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral-type benzodiazepine receptor | TSPO_MOUSE | Tspo
Type:
PROTEIN
Mol. Mass.:
18845.65
Organism:
Mus musculus
Description:
ChEMBL_39280
Residue:
169
Sequence:
MPESWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIVWKELGGFTEDAMVPLGLYTGQLALNWAWPPIFFGARQMGWALADLLLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATVLNYYVWRDNSGRRGGSRLPE
  
Inhibitor
Name:
BDBM50045877
Synonyms:
2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylacetamide | 2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dihexyl-acetamide | CHEMBL63154 | [N,N-di-n-hexyl-2-(4-fluorophenyl) indole-3-acetamide]
Type:
Small organic molecule
Emp. Form.:
C28H37FN2O
Mol. Mass.:
436.6046
SMILES:
CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Structure:
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