Reaction Details
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Reverse transcriptase
Ligand
BDBM50501787
Substrate
n/a
Meas. Tech.
ChEMBL_1704120 (CHEMBL4055353)
IC50
89000±n/a nM
Citation
Ferro, S; Buemi, MR; De Luca, L; Agharbaoui, FE; Pannecouque, C; Monforte, AM Searching for novel N Bioorg Med Chem 25:3861-3870 (2017) [PubMed] Article More Info.:
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
Inhibitor
Name:
BDBM50501787
Synonyms:
CHEMBL4079079
Type:
Small organic molecule
Emp. Form.:
C16H15ClN2O3S
Mol. Mass.:
350.82
SMILES:
Cc1ccc(CCS(=O)(=O)n2c3cc(Cl)ccc3[nH]c2=O)cc1
Structure:
