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Target
D(2) dopamine receptor
Ligand
BDBM50029340
Substrate
n/a
Meas. Tech.
ChEMBL_62079 (CHEMBL672378)
Ki
4130±n/a nM
Citation
 Shah, JH; Kline, RH; Geter-Douglass, B; Izenwasser, S; Witkin, JM; Newman, AH (+/-)-3-[4'-(N,N-dimethylamino)cinnamyl]benzazepine analogs: novel dopamine D1 receptor antagonists. J Med Chem 39:3423-8 (1996) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50029340
Synonyms:
8-Chloro-3-(6-dimethylamino-hexyl)-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol | CHEMBL108764
Type:
Small organic molecule
Emp. Form.:
C24H33ClN2O
Mol. Mass.:
400.985
SMILES:
CN(C)CCCCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: