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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50029522
Substrate
n/a
Meas. Tech.
ChEMBL_157546 (CHEMBL764930)
Ki
>2000±n/a nM
Citation
 Romines, KR; Morris, JK; Howe, WJ; Tomich, PK; Horng, MM; Chong, KT; Hinshaw, RR; Anderson, DJ; Strohbach, JW; Turner, SR; Mizsak, SA Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationships. J Med Chem 39:4125-30 (1996) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50029522
Synonyms:
4-Hydroxy-3-(1-phenyl-propyl)-6,7,8,9,10,11-hexahydro-5H-cyclonona[b]pyran-2-one | CHEMBL132747
Type:
Small organic molecule
Emp. Form.:
C21H26O3
Mol. Mass.:
326.4293
SMILES:
CCC(c1ccccc1)c1c(O)c2CCCCCCCc2oc1=O
Structure:
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