Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50054468
Substrate
n/a
Meas. Tech.
ChEMBL_46807 (CHEMBL659694)
Ki
1690±n/a nM
Citation
 Khanolkar, AD; Abadji, V; Lin, S; Hill, WA; Taha, G; Abouzid, K; Meng, Z; Fan, P; Makriyannis, A Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand. J Med Chem 39:4515-9 (1996) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50054468
Synonyms:
(5Z,8Z,11Z,14Z)-1-(3-Hydroxy-piperidin-1-yl)-icosa-5,8,11,14-tetraen-1-one | CHEMBL140773
Type:
Small organic molecule
Emp. Form.:
C25H41NO2
Mol. Mass.:
387.5985
SMILES:
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)N1CCCC(O)C1
Structure:
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