Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50504632
Substrate
n/a
Meas. Tech.
ChEMBL_1815851 (CHEMBL4315425)
Ki
28±n/a nM
Citation
 Temme, L; Börgel, F; Schepmann, D; Robaa, D; Sippl, W; Daniliuc, C; Wünsch, B Impact of hydroxy moieties at the benzo[7]annulene ring system of GluN2B ligands: Design, synthesis and biological evaluation. Bioorg Med Chem 27:0 (2019) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50504632
Synonyms:
CHEMBL4561134
Type:
Small organic molecule
Emp. Form.:
C20H26ClNO
Mol. Mass.:
331.88
SMILES:
Cl.OC1CC(CCc2ccccc12)NCCCc1ccccc1
Structure:
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