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Target
Integrase
Ligand
BDBM50057339
Substrate
n/a
Meas. Tech.
ChEMBL_90715 (CHEMBL702114)
IC50
172300±n/a nM
Citation
 Zhao, H; Neamati, N; Mazumder, A; Sunder, S; Pommier, Y; Burke, TR Arylamide inhibitors of HIV-1 integrase. J Med Chem 40:1186-94 (1997) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50057339
Synonyms:
6-Hydroxy-naphthalene-2-carboxylic acid | CHEMBL278950
Type:
Small organic molecule
Emp. Form.:
C11H8O3
Mol. Mass.:
188.1794
SMILES:
OC(=O)c1ccc2cc(O)ccc2c1
Structure:
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