Reaction Details Report a problem with these data
Target
Melatonin receptor type 1C
Ligand
BDBM50472142
Substrate
n/a
Meas. Tech.
ChEMBL_1824703 (CHEMBL4324467)
Ki
0.378000±n/a nM
Citation
 Wang, SY; Shi, XC; Laborda, P Indole-based melatonin analogues: Synthetic approaches and biological activity. Eur J Med Chem 185:0 (2020) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1C
Synonyms:
CKB | MTR1C_CHICK | Mel-1C-R | Mel1c receptor | Melatonin receptor type 1C
Type:
PROTEIN
Mol. Mass.:
38595.98
Organism:
Gallus gallus
Description:
ChEMBL_104739
Residue:
346
Sequence:
MERPGSNGSCSGCRLEGGPAARAASGLAAVLIVTIVVDVLGNALVILSVLRNKKLRNAGNIFVVSLSVADLVVAVYPYPLILSAIFHNGWTMGNIHCQISGFLMGLSVIGSIFNITAIAINRYCYICHSLRYDKLFNLKNTCCYICLTWTLTVVAIVPNFFVGSLQYDPRIYSCTFAQTVSTSYTITVVVVHFIVPLSIVTFCYLRIWILVIQVKHRVRQDCKQKIRAADIRNFLTMFVVFVLFAVCWGPLNFIGLAVSINPSKVQPHIPEWLFVLSYFMAYFNSCLNAVIYGLLNQNFRKEYKRILLMLRTPRLLFIDVSKGGTEGLKSKPSPAVTNNNQAEIHL
  
Inhibitor
Name:
BDBM50472142
Synonyms:
CHEMBL142343
Type:
Small organic molecule
Emp. Form.:
C19H26N2O2
Mol. Mass.:
314.4219
SMILES:
CCCC(=O)NCC1CCCc2c1c1cc(OC)ccc1n2C
Structure:
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