Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50061327
Substrate
n/a
Meas. Tech.
ChEMBL_60661 (CHEMBL671698)
Ki
1.2±n/a nM
Citation
 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD (Aryloxy)alkylamines as selective human dopamine D4 receptor antagonists: potential antipsychotic agents. J Med Chem 40:4026-9 (1998) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50061327
Synonyms:
(2-p-Tolyloxy-ethyl)-(3-m-tolyloxy-propyl)-amine | CHEMBL435598
Type:
Small organic molecule
Emp. Form.:
C19H25NO2
Mol. Mass.:
299.4073
SMILES:
Cc1ccc(OCCNCCCOc2cccc(C)c2)cc1
Structure:
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