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Target
Serine protease 1
Ligand
BDBM50062031
Substrate
n/a
Meas. Tech.
ChEMBL_210650 (CHEMBL811612)
Ki
110±n/a nM
Citation
 Maduskuie, TP; McNamara, KJ; Ru, Y; Knabb, RM; Stouten, PF Rational design and synthesis of novel, potent bis-phenylamidine carboxylate factor Xa inhibitors. J Med Chem 41:53-62 (1998) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM50062031
Synonyms:
3-(3-Carbamimidoyl-phenyl)-5-(4-methanesulfonylamino-phenyl)-pentanoic acid methyl ester | CHEMBL436026
Type:
Small organic molecule
Emp. Form.:
C20H25N3O4S
Mol. Mass.:
403.495
SMILES:
COC(=O)CC(CCc1ccc(NS(C)(=O)=O)cc1)c1cccc(c1)C(N)=N
Structure:
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