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Target
Prolyl 4-hydroxylase
Ligand
BDBM50510129
Substrate
n/a
Meas. Tech.
ChEMBL_1840409 (CHEMBL4340708)
IC50
15700±n/a nM
Citation
 Langley, GW; Abboud, MI; Lohans, CT; Schofield, CJ Inhibition of a viral prolyl hydroxylase. Bioorg Med Chem 27:2405-2412 (2019) [PubMed]  Article 
Target
Name:
Prolyl 4-hydroxylase
Synonyms:
A085R | Prolyl 4-hydroxylase
Type:
PROTEIN
Mol. Mass.:
27815.10
Organism:
Paramecium bursaria Chlorella virus 1
Description:
ChEMBL_119118
Residue:
242
Sequence:
MTNKFISYNKMETREYLLTILFVIACFMVLNLERREGFETSDRPGVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIKSEVGGATENDPIKLDPKSRNSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAVK
  
Inhibitor
Name:
BDBM50510129
Synonyms:
CHEMBL4475458
Type:
Small organic molecule
Emp. Form.:
C13H8N2O3
Mol. Mass.:
240.2142
SMILES:
OC(=O)c1c[nH]c2c(ccc3cccnc23)c1=O
Structure:
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