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Target
Prolyl 4-hydroxylase
Ligand
BDBM26121
Substrate
n/a
Meas. Tech.
ChEMBL_1840409 (CHEMBL4340708)
IC50
>1000000±n/a nM
Citation
 Langley, GW; Abboud, MI; Lohans, CT; Schofield, CJ Inhibition of a viral prolyl hydroxylase. Bioorg Med Chem 27:2405-2412 (2019) [PubMed]  Article 
Target
Name:
Prolyl 4-hydroxylase
Synonyms:
A085R | Prolyl 4-hydroxylase
Type:
PROTEIN
Mol. Mass.:
27815.10
Organism:
Paramecium bursaria Chlorella virus 1
Description:
ChEMBL_119118
Residue:
242
Sequence:
MTNKFISYNKMETREYLLTILFVIACFMVLNLERREGFETSDRPGVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIKSEVGGATENDPIKLDPKSRNSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAVK
  
Inhibitor
Name:
BDBM26121
Synonyms:
SUCCINIC ACID | Substrate analogue, 11 | Succinate | Succinic acid, 6 | butanedioic acid | succinate, 9
Type:
Small organic molecule
Emp. Form.:
C4H6O4
Mol. Mass.:
118.088
SMILES:
OC(=O)CCC(O)=O
Structure:
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