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Target
Prolyl 4-hydroxylase
Ligand
BDBM118338
Substrate
n/a
Meas. Tech.
ChEMBL_1840409 (CHEMBL4340708)
IC50
2500±n/a nM
Citation
 Langley, GW; Abboud, MI; Lohans, CT; Schofield, CJ Inhibition of a viral prolyl hydroxylase. Bioorg Med Chem 27:2405-2412 (2019) [PubMed]  Article 
Target
Name:
Prolyl 4-hydroxylase
Synonyms:
A085R | Prolyl 4-hydroxylase
Type:
PROTEIN
Mol. Mass.:
27815.10
Organism:
Paramecium bursaria Chlorella virus 1
Description:
ChEMBL_119118
Residue:
242
Sequence:
MTNKFISYNKMETREYLLTILFVIACFMVLNLERREGFETSDRPGVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIKSEVGGATENDPIKLDPKSRNSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAVK
  
Inhibitor
Name:
BDBM118338
Synonyms:
US8653111, 62
Type:
Small organic molecule
Emp. Form.:
C15H16N6O3
Mol. Mass.:
328.3259
SMILES:
CC(C)(C)OC(=O)c1ccc(nc1)-n1[nH]cc(-n2ccnn2)c1=O
Structure:
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