Reaction Details Report a problem with these data
Target
Cytidine deaminase
Ligand
BDBM50065261
Substrate
n/a
Meas. Tech.
ChEMBL_52536 (CHEMBL665308)
Ki
100000±n/a nM
Citation
 Jeong, LS; Buenger, G; McCormack, JJ; Cooney, DA; Hao, Z; Marquez, VE Carbocyclic analogues of the potent cytidine deaminase inhibitor 1-(beta-D-ribofuranosyl)-1,2-dihydropyrimidin-2-one (zebularine). J Med Chem 41:2572-8 (1998) [PubMed]  Article 
Target
Name:
Cytidine deaminase
Synonyms:
CDA | CDD | CDD_HUMAN | Cytidine deaminase | Cytidine deaminase (CDA)
Type:
Ezyme
Mol. Mass.:
16185.04
Organism:
Homo sapiens (Human)
Description:
P32320
Residue:
146
Sequence:
MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ
  
Inhibitor
Name:
BDBM50065261
Synonyms:
1-((4R,5S)-4,5-Dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one | CHEMBL315242
Type:
Small organic molecule
Emp. Form.:
C10H12N2O4
Mol. Mass.:
224.2133
SMILES:
OCC1=CC([C@H](O)[C@@H]1O)n1cccnc1=O |t:2|
Structure:
Search PDB for entries with ligand similarity: