Reaction Details Report a problem with these data
Target
G-protein coupled receptor 84
Ligand
BDBM50239186
Substrate
n/a
Meas. Tech.
ChEMBL_1843335 (CHEMBL4343762)
EC50
500±n/a nM
Citation
 Köse, M; Pillaiyar, T; Namasivayam, V; De Filippo, E; Sylvester, K; Ulven, T; von Kügelgen, I; Müller, CE An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights. J Med Chem 63:2391-2410 (2020) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 84
Synonyms:
EX33 | G-protein coupled receptor 84 | GPR84 | GPR84_HUMAN | Inflammation-related G-protein coupled receptor EX33
Type:
PROTEIN
Mol. Mass.:
43726.73
Organism:
Homo sapiens (Human)
Description:
ChEMBL_116040
Residue:
396
Sequence:
MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
  
Inhibitor
Name:
BDBM50239186
Synonyms:
1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmethane | 3,3-Diindolylmethane | Arundine | CHEBI:50182 | Diindolylmethane
Type:
Small organic molecule
Emp. Form.:
C17H14N2
Mol. Mass.:
246.3065
SMILES:
C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Structure:
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