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Target
Oxytocin receptor
Ligand
BDBM50066092
Substrate
n/a
Meas. Tech.
ChEMBL_149203 (CHEMBL759542)
IC50
68±n/a nM
Citation
 Nargund, RP; Patchett, AA; Bach, MA; Murphy, MG; Smith, RG Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential. J Med Chem 41:3103-27 (1998) [PubMed]  Article 
Target
Name:
Oxytocin receptor
Synonyms:
OT-R | OXTR | OXYR_HUMAN | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42793.26
Organism:
Homo sapiens (Human)
Description:
Oxytocin OXTR HEK293::B2R9L7
Residue:
389
Sequence:
MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
  
Inhibitor
Name:
BDBM50066092
Synonyms:
3N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1-ylsulfonylmethylbicyclo[2.2.1]hept-2-yl]hexahydro-3-pyridinecarboxamide | CHEMBL277400 | L-368112
Type:
Small organic molecule
Emp. Form.:
C29H43N3O3S
Mol. Mass.:
513.735
SMILES:
CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc34)CC1)C(C2)NC(=O)C1CCCNC1 |THB:27:25:1:5.4|
Structure:
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