Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50511964
Substrate
n/a
Meas. Tech.
ChEMBL_1846293 (CHEMBL4346834)
Ki
>1000±n/a nM
Citation
 Jiang, J; Seel, CJ; Temirak, A; Namasivayam, V; Arridu, A; Schabikowski, J; Baqi, Y; Hinz, S; Hockemeyer, J; Müller, CE A J Med Chem 62:4032-4055 (2019) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50511964
Synonyms:
CHEMBL4530074
Type:
Small organic molecule
Emp. Form.:
C25H27ClN6O5S
Mol. Mass.:
559.037
SMILES:
CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1ccc(OC)c(Cl)c1
Structure:
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