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Target
Virulence factor transcriptional regulator MvfR
Ligand
BDBM50512171
Substrate
n/a
Meas. Tech.
ChEMBL_1848045 (CHEMBL4348586)
IC50
1200±n/a nM
Citation
 Soheili, V; Tajani, AS; Ghodsi, R; Bazzaz, BSF Anti-PqsR compounds as next-generation antibacterial agents against Pseudomonas aeruginosa: A review. Eur J Med Chem 172:26-35 (2019) [PubMed]  Article 
Target
Name:
Virulence factor transcriptional regulator MvfR
Synonyms:
Transcriptional regulator MvfR
Type:
PROTEIN
Mol. Mass.:
37217.11
Organism:
Pseudomonas aeruginosa PA14
Description:
ChEMBL_107649
Residue:
332
Sequence:
MPIHNLNHVNMFLQVIASGSISSAARILRKSHTAVSSAVSNLEIDLCVELVRRDGYKVEPTEQALRLIPYMRSLLNYQQLIGDIAFNLNKGPRNLRVLLDTAIPPSFCDTVSSVLLDDFNMVSLIRTSPADSLATIKQDNAEIDIAITIDEELKISRFNQCVLGYTKAFVVAHPQHPLCNASLHSIASLANYRQISLGSRSGQHSNLLRPVSDKVLFVENFDDMLRLVEAGVGWGIAPHYFVEERLRNGTLAVLSELYEPGGIDTKVYCYYNTALESERSFLRFLESARQRLRELGRQRFDDAPAWQPSIVETAQRRSGPKALAYRQRAAPE
  
Inhibitor
Name:
BDBM50512171
Synonyms:
CHEMBL4513689
Type:
Small organic molecule
Emp. Form.:
C17H23F2N3O
Mol. Mass.:
323.3808
SMILES:
CCCCCCCCCc1nc2cc(F)c(F)cc2c(=O)n1N
Structure:
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